| Item Type | Name |
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Concept
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Drug Resistance
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Concept
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Enzyme Induction
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Concept
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Scleroderma, Systemic
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Concept
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Drug Resistance, Neoplasm
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Concept
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Lupus Erythematosus, Systemic
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Concept
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Hypoxia-Inducible Factor 1, alpha Subunit
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Concept
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Angiogenesis Inducing Agents
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Concept
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Vascular Resistance
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Concept
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Ventilator-Induced Lung Injury
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Academic Article
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Differential distribution of electrophysiologically distinct myocytes in conduit and resistance arteries determines their response to nitric oxide and hypoxia.
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Academic Article
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Oxygen-induced constriction of rabbit ductus arteriosus occurs via inhibition of a 4-aminopyridine-, voltage-sensitive potassium channel.
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Academic Article
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Ventilation-induced pulmonary vasodilation at birth is modulated by potassium channel activity.
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Academic Article
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Impairment of hypoxic pulmonary vasoconstriction in mice lacking the voltage-gated potassium channel Kv1.5.
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Academic Article
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Nitric oxide deficiency in fenfluramine- and dexfenfluramine-induced pulmonary hypertension.
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Academic Article
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Vitamin A decreases the incidence and severity of nitrofen-induced congenital diaphragmatic hernia in rats.
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Academic Article
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Dexfenfluramine elevates systemic blood pressure by inhibiting potassium currents in vascular smooth muscle cells.
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Academic Article
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O2 sensing is preserved in mice lacking the gp91 phox subunit of NADPH oxidase.
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Academic Article
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In vivo gene transfer of the O2-sensitive potassium channel Kv1.5 reduces pulmonary hypertension and restores hypoxic pulmonary vasoconstriction in chronically hypoxic rats.
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Academic Article
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Cellular and molecular pathobiology of pulmonary arterial hypertension.
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Academic Article
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Oral sildenafil is an effective and specific pulmonary vasodilator in patients with pulmonary arterial hypertension: comparison with inhaled nitric oxide.
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Academic Article
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Hypoxic fetoplacental vasoconstriction in humans is mediated by potassium channel inhibition.
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Academic Article
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Long-term treatment with oral sildenafil is safe and improves functional capacity and hemodynamics in patients with pulmonary arterial hypertension.
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Academic Article
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Vascular endothelial growth factor gene therapy increases survival, promotes lung angiogenesis, and prevents alveolar damage in hyperoxia-induced lung injury: evidence that angiogenesis participates in alveolarization.
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Academic Article
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An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities to human pulmonary arterial hypertension.
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Academic Article
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Overexpression of human bone morphogenetic protein receptor 2 does not ameliorate monocrotaline pulmonary arterial hypertension.
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Academic Article
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Hypoxic pulmonary vasoconstriction: redox regulation of O2-sensitive K+ channels by a mitochondrial O2-sensor in resistance artery smooth muscle cells.
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Academic Article
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Preferential expression and function of voltage-gated, O2-sensitive K+ channels in resistance pulmonary arteries explains regional heterogeneity in hypoxic pulmonary vasoconstriction: ionic diversity in smooth muscle cells.
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Academic Article
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ZK 36-374, a stable analog of prostacyclin, prevents acute hypoxic pulmonary hypertension in the dog.
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Academic Article
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Detection of activated O2 species in vitro and in rat lungs by chemiluminescence.
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Academic Article
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Oxygen activates the Rho/Rho-kinase pathway and induces RhoB and ROCK-1 expression in human and rabbit ductus arteriosus by increasing mitochondria-derived reactive oxygen species: a newly recognized mechanism for sustaining ductal constriction.
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Academic Article
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Diagnosis and management of pulmonary hypertension in systemic sclerosis.
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Academic Article
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Hypoxic pulmonary vasoconstriction is unaltered by creatine depletion induced by dietary beta-guanidino propionic acid.
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Academic Article
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Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension.
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Academic Article
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The effects of substance P on the preconstricted pulmonary vasculature of the anesthetized dog.
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Academic Article
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Chronic EDRF inhibition and hypoxia: effects on pulmonary circulation and systemic blood pressure.
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Academic Article
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A KCNE1 missense variant (V47I) causing exercise-induced long QT syndrome (Romano Ward).
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Academic Article
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Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension.
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Academic Article
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Effect of graded hypoxia on the induction and function of inducible nitric oxide synthase in rat mesangial cells.
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Academic Article
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Redox status in the control of pulmonary vascular tone.
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Academic Article
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Cellular and molecular basis of pulmonary arterial hypertension.
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Academic Article
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Potassium channels regulate tone in rat pulmonary veins.
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Academic Article
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Hypoxic pulmonary vasoconstriction.
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Academic Article
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Mitochondrial metabolism, redox signaling, and fusion: a mitochondria-ROS-HIF-1alpha-Kv1.5 O2-sensing pathway at the intersection of pulmonary hypertension and cancer.
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Academic Article
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A proposed mitochondrial-metabolic mechanism for initiation and maintenance of pulmonary arterial hypertension in fawn-hooded rats: the Warburg model of pulmonary arterial hypertension.
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Academic Article
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Pulmonary and systemic nitric oxide measurements during CCK-5-induced panic attacks.
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Academic Article
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Atrioventricular heart block and syncope coincident with diagnosis of systemic lupus erythematosus.
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Academic Article
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Ischemia-induced Drp1 and Fis1-mediated mitochondrial fission and right ventricular dysfunction in pulmonary hypertension.
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Academic Article
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Abnormal angiogenesis in blood outgrowth endothelial cells derived from von Willebrand disease patients.
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Academic Article
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Survival in pulmonary hypertension due to chronic lung disease: Influence of low diffusion capacity of the lungs for carbon monoxide.
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Academic Article
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Resistance over compliance describes right ventricular afterload better than resistance-compliance time: a friendly amendment.
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Academic Article
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Emerging concepts in the molecular basis of pulmonary arterial hypertension: part I: metabolic plasticity and mitochondrial dynamics in the pulmonary circulation and right ventricle in pulmonary arterial hypertension.
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Academic Article
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Hypoxic Pulmonary Vasoconstriction: From Molecular Mechanisms to Medicine.
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Academic Article
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Activation of the EGFR/p38/JNK pathway by mitochondrial-derived hydrogen peroxide contributes to oxygen-induced contraction of ductus arteriosus.
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Academic Article
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Pediatric Pulmonary Hypertension: Guidelines From the American Heart Association and American Thoracic Society.
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Academic Article
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Ndufs2, a Core Subunit of Mitochondrial Complex I, Is Essential for Acute Oxygen-Sensing and Hypoxic Pulmonary Vasoconstriction.
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Academic Article
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Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat.
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Academic Article
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Epigenetic Metabolic Reprogramming of Right Ventricular Fibroblasts in Pulmonary Arterial Hypertension: A Pyruvate Dehydrogenase Kinase-Dependent Shift in Mitochondrial Metabolism Promotes Right Ventricular Fibrosis.
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Academic Article
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PINK1-induced phosphorylation of mitofusin 2 at serine 442 causes its proteasomal degradation and promotes cell proliferation in lung cancer and pulmonary arterial hypertension.
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Academic Article
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Inhibiting pyruvate kinase muscle isoform 2 regresses group 2 pulmonary hypertension induced by supra-coronary aortic banding.
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Academic Article
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Mitochondrial fission links ECM mechanotransduction to metabolic redox homeostasis and metastatic chemotherapy resistance.
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Academic Article
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An integrated proteomic and transcriptomic signature of the failing right ventricle in monocrotaline induced pulmonary arterial hypertension in male rats.
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Grant
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Impaired mitochondrial fusion in pulmonary arterial hypertension
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Grant
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O2 sensing in the human and rabbit ductus arteriosus.
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Grant
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EDRF IN NORMAL AND HYPERTENSIVE PULMONARY VASCULATURE
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Grant
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The Role of DRP-1 and Mitochondrial Fission in Pulmonary Arterial Hypertension
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